AJHG

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? RD: Revisionist circles in African anthropology were having important discussions about how we understand ethnicity of past groups in Southern Africa. One big take-home message was that some labels used in historic texts have been mistakenly taken... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? SI: Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable disease that causes spinal canal stenosis leading to myelopathy and/or radiculopathy. OPLL is a common disease. Its prevalence is more than 2% in... Read More

Inside AJHG: A Chat with Mitchell Machiela KS: What motivated you to start working on this project? MM: Our main motivation for this study was to better understand how germline genetic variation in the 6p25.1 Ewing sarcoma (EwS) susceptibility locus contributes to EwS risk. Specifically, based on evidence from a prior investigation of the 10q21.3... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What prompted you to start working on this project?  RG: I needed to find some G6PD variants with a range of activities for an experiment I was planning. As I was reading the literature, I was finding reviews and following the trails back to the original... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? PL: My background is the study of the causes and mechanisms of neurogenetic conditions. A part of this has been the identification of novel genetic mechanisms causing ataxia, a condition where individuals have impaired balance and coordination.... Read More