A Transchromosomic Rat Model of Down Syndrome

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Description

This month’s presentation is on the recent AJHG paper, “A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features.” Attendees will have the opportunity to ask questions in a live Q&A session. 

Overview of Presentation

  • Trisomy 21 is among the most complex genetic challenges to development and function
  • Animal models are essential to understanding mechanisms underlying divergent features
  • New models provide improved genetic representation and expand opportunities for preclinical studies

To read the full paper, check the Journal Paper tab.

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