Posted By: HGG Advances HGGA: What motivated you to start working on this project? Jayati Sharma (JS): I have been interested in how our genetics and environment interact to affect our overall physical health for a long time. Given the significant disparities in the health profiles of different minoritized populations in the United States, I... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? Anne Gregor (AG): I first became interested in FBXO11, when we and others could link variants in this gene to a variable neurodevelopmental disorder (NDD). As not much was known about neuronal functions of the ubiquitin ligase complex protein FBXO11 and... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? LM: Polygenic risk scores (PRS) have been a hot topic in the field of complex disorders for several years now, and they continue to be topical as new methods and datasets emerge to aid in improving the prediction accuracy of these... Read More